Quick answer
Shoot the underside weak point and reset at the cave entrance
Black Caiman takes much better damage on the underside from the middle of its neck through the upper belly. Open with sniper mode while it is unaware, then move below it as it leaves the cave.
When it chases, retreat a short distance beyond the den, dodge the tail sweep, and wait for the question-mark disengage. Move back under the returning caiman for another weak-point volley.
Use Black Caiman ingredients wisely
The predator is a key target for the Taste of Fish VIP chain and premium Grill cooking. Harvest meat on repeat dives for Black Caiman Tacos; do not base a repeatable menu around a limited tail reward if the recipe consumes it faster than it can be replaced.
FAQ
Black Caiman questions
Where is Black Caiman's weak point?
Aim at the underside from the middle of its neck through the upper belly. The damage difference is significant.
What is the best weapon for Black Caiman?
Sniper mode is the safest. An upgraded shotgun is faster when you can remain under the belly without being hit by the turn or tail.